Chemicals from our phone and TV screens are accumulating in the brains of endangered dolphins and porpoises. New research shows these "liquid crystal monomers" from e-waste can cross the blood-brain barrier and may disrupt DNA repair, highlighting the growing impact of electronics on marine life.

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比如,和誉医药的第二代FGFR小分子抑制剂ABSK061,在降低对FGFR1抑制的同时,保持对FGFR2/3高选择性,理论上安全性更高。在动物模型中,ABSK061的表现优于Infigratinib,目前ABSK061治疗3-12岁ACH儿童患者的2期临床正在进行中。

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